BIO 3124 Lecture Notes - Lecture 13: Immunodeficiency, Lactobacillus Plantarum, Bacterial Vaginosis
Document Summary
Live microbial feed supplements that have bene cial effects on the host by improving its intestinal microbial balance. Mother"s microbiota: maternal vaginal and intestinal ora constitutes the source of bacteria that colonize the investing of the new born. Natural: more bene cial - newborn will acquire the mother"s microbiota. C-section: won"t acquire mother"s microorganisms, will acquire the environment"s. Birth environment: microorganisms in the environment can contribute to the newborn"s microbiota. Most of our food is sterile - causes weak and homogenous microbiota. Able to attach to the intestinal epithelia and colonize. Able to utilize nutrients in a normal diets. Capable of exerting a bene cial effect on the host. Will educate and prevent immune system from overreacting, teaches it to recognize things that are much more dangerous. Adherence and stimulation of immune system: enhance secretory antibodies that can then act against other pathogens. Competition for adhesion sites and essential nutrients: competes with pathogens - prevents them from easily colonizing intestine.
