BIO 3153 Lecture Notes - Lecture 8: Phosphatidylinositol (3,4,5)-Trisphosphate, Cytosol, Conformational Change
24 Jan 2018
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October 3rd, 2017: the origin of the signal originates outside the cell, this will have an effect on the cell cycle regulation. Total cell mass (2: what regulates total cell mass, there are 3 main types, mitogens promote mitosis. It"s hard to (cid:272)hara(cid:272)terize the(cid:373) as for e(cid:454)a(cid:373)ple, (cid:373)itoge(cid:374)s (cid:272)a(cid:374) also (cid:272)ause sur(cid:448)i(cid:448)al fa(cid:272)tors. Increase the number of cell division: survival factors. Increase growth proteins: originates from outside, gfs bind to cell receptors and initiate pathways that occur inside the cell, although its extracellular, we can still talk about intracellular pathways. In the presence of atp, each of the subunit phosphorylates the other: after phosphorylation, other proteins are recruited to broadcast the signal. Nerve growth factor (ngf: neurotrophin is a class of protein secreted by nerve tissues, they attract nerve cells, ngf is a neurotrophin. Mitogens: promotes mitosis, promotes cyclins in the cell to go all the way around the cycle (not just mitosis)
