BIO 3302 Lecture Notes - Lecture 15: Renal Corpuscle, Teleost, Distal Convoluted Tubule

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Mid 2 from lec 10 to nov 16. Lowest rcr inulin, na, gluc, urea (cid:271)/(cid:272) it"s (cid:272)o(cid:373)pletely rea(cid:271)sor(cid:271)ed, (cid:374)o glu(cid:272) i(cid:374) uri(cid:374)e, rcr=0. Diabetes: loss of gluc in urine, higher rcr. Cap bed w high sa for filt, afferent is short and large for low r pathway, efferent small windy leads to other cap, high r pathway for bp to drive filt. Why/how marine teleost fish restrict filt: dehydrating enviro prob w water loss, filt causes urine inc water loss, few nephrons smaller renal corpuscle, some aglom and rely on secretion for waste removal no filt. Do(cid:374)"t (cid:374)eed to (cid:449)orry a(cid:271)out (cid:449)ater loss, osmolarity that is on par or above enviro, accum urea and tmao, isosmotic to enviro. Fw fish large glom and renal corpuscle, distal tubule dilutes urine marine want to conserve water not get rid. Pink salt: low vol of very salty urine, high osmo conc.