BPS 1101 Lecture Notes - Lecture 1: Diphenhydramine, Chlorphenamine, Insulin

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 1101
• Professor: William Ogilvie

Document Summary

Drugs 101 drugs in the body part 1: Drug metabolized by the body: drug enters body, drugs must pass through many body defense barriers that guard the body a. stomach; b. liver; c. intestine. Drugs pass through one end (water) of cell to other side (blood) =>chem environ inside changes to oily: drug molecules pass through membrane when passing cell body; [membrane: semi solid oil/water] Drugs pass thru 1 extremely chemical environmental to another [water-oil-water/blood] Liver chemically metabolize/modifies drug molecule chemical structure to help body eliminate it. Required factors to make sure drug passes through => Drugs pass many barriers to reach target organ & less drugs reach target: ensure sufficient amount of drugs reach target = drug interact with biological molecules. Drugs work by physically touching body molecules at threshold to produce biological effect. = all biological effects caused by drug molecules touching body molecules. Drug quantity/amount determine if molecules will stick & nake substance a drug