HSS 1100 Lecture Notes - Lecture 8: Stool Test, Croup, Syncytium
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Require living cells for growth and replication ( cell cultures, eggs, animals/plants) Multiply by separate synthesis of nucleic acid and protein, combine to forms virus particles. > replication: adsorption, penetration and uncoating, nucleic acid and protein synthesis, assembly, release. > how de we detect viral infections: detect the virus itself, detect the immune response antibodies against the virus. > viral diagnosis: detection in clinical specimens, visualisation by electron microscopy, cell culture, detection of patients immune response, antibody detection, presence or absence (elisa); immunity test, rise in antibody titre or high antibody titre; diagnostic test. > what types of viruses will we learn about: viruses of the breathing, enteric viruses, viruses of diarrhea, viruses of the rashes. Different families: influenza viruses, parainfluenza viruses, respiratory syncytial viruses, rhinoviruses, adenoviruses, echoviruses, coxsackie viruses, herpes viruses. Throat washings, naso-pharyngeal aspirate inoculated into cell culture. Annual vaccination especially for high risk groups. * the who pandemic response and planning is a direct reflection of disease.