HSS 1101 Lecture Notes - Humoral Immunity, Antibiotics, Antigen
Document Summary
Immunity: the protection against infectious disease conferred by immunization, previous exposure body"s natural ability to resist infection. Skin: mechanical barrier; slightly acidic due to sweat (bactericidal); low/suboptimal temperature. Mucous membranes: mechanical barrier; lysosomes in secretions (eg. tears); Iron binding proteins: proteins collect and recycle iron for use in blood, limiting supply of iron for bacteria. Phagocytosis: cells swallow and lyse bacteria; example macrophages, pmns, monocytes. Complement: series of steps that produce plasma proteins which kill invaders; non-specific. Immunity induced in the body as a result of encounters with invaders. Has 2 main systems of protection, humeral and cell mediated (cmi) 1. 5 humoral immunity: consists of specific circulating antibodies, also called immunoglobulins or igs; produced by b-lymphocytes/plasma cells when exposed to a specific antigen (non self); variable region recognizes antigen, constant region chills. 1. 11 there are 5 types of antibody: g a m e d. Igg: host defence; can cross placenta to protect newborn.
