HSS 3106 Lecture Notes - Lecture 16: Necrosis, Streptokinase, Asthma
6 Apr 2017
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Do not dissolve clots already formed, but may prevent clots from becoming larger. Used to treat mi, venous thrombosis, pulmonary emboli. All oral anticoagulants act by producing a functional deficiency of vitamin k, thereby impairing the normal synthesis of factors ii, vii, ix, Primarily used for thrombosis in veins and x. All, except dicumarolm are well absorbed after oral administration. They come in tablet and injectable forms. Inhibitors of clotting factor synthesis: these anticoagulants inhibit the production of certain clotting factors in the liver. Inhibitors of thrombin: these drugs interfere with blood clotting by blocking the activity of thrombin. They include heparin and lepirudin (refludan: antiplatelet drugs: these drugs interact with platelets, which is a type of blood cell, to block platelets from aggregating into harmful clots. They include aspirin, ticlopidine (ticlid), clopidogrel (plavix), tirofiban (aggrastat), and eptifibatide (integrilin) Works by increasing length of coagulation; inhibits thrombi from forming or growing larger.
