HSS 3305 Lecture Notes - Lecture 14: Bicuspid Aortic Valve, Vegf Receptor, Hypertensive Heart Disease

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 3305
• Professor: Karen Philips

Document Summary

Narrowing of peripheral arterioles, high pressure pump, high resistance. Malfunctioning pump: mechanical analogies; see examples of mechanisms of the disease, could be caused by environmental factors, genetic factors, many implications from heart problems. Electrical: ecg or ekg; gives signal if the rhythm is normal; pwrs rhythm becomes abnormal (arrhythmia), so(cid:373)ethi(cid:374)g"s wrong, depolarization of atria; ventricles big spike and recovery. Congenital heart disease: present from birth, or may occur as deficiency during development, abnormalities: defective partitions between chambers, malformed cardiac valves, large vessels entering/leaving heart may not be positioned correctly, (cid:862)fault(cid:455) pu(cid:373)p (cid:272)o(cid:374)stru(cid:272)tio(cid:374)(cid:863)- actual defect in heart structure. Tetralogy of fallot: 4 defects in 1: Ventricular septum defect: hole in the septum, inappropriate mixing of blood into the left ventricle. Pulmonary stenosis: where it should be going to the lung, have thickening (narrowing), enlarged, stenosis is thickening/calcification, where the blood should lea(cid:448)e a(cid:374)d go to the lu(cid:374)gs (cid:271)ut (cid:271)e(cid:272)ause of the thi(cid:272)ke(cid:374)i(cid:374)g there is(cid:374)"t as (cid:373)u(cid:272)h (cid:271)lood flow.