HSS 3505 Lecture Notes - Lecture 11: Polycystin 2, Colorectal Cancer, Basal-Cell Carcinoma
8 Dec 2016
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Document Summary
Fluid regulation: blood pressure, cardiovascular output, imbalances. Edema: acid/base balance, waste elimination, drug excretion pharmacology. Nephrons: functional units located in renal cortex: renal corpuscle: filtering unit with glomerulus and glomerular capsule, renal tubule: proximal convulated tubule, loop of henle, distal convulated tubule. Urine production promotes homeostasis by regulating volume and composition of blood three organic waste products: urea: most abundant waste, creatinine: produced in skeletal muscle tissue, uric acid: formed by recycling nitrogenous base from rna molecules. Kidneys return filtered fluid to internal environment through tubular reabsorption. Waste products are excreted in urine tubular secretion removes hydrogen ions and toxins faster than through filtration. Acquired: diabetic nephropathy, glomerulonephritis, kidney stones, kidney tumors. Renal cell carcinoma: pyelonephritis, renal failure. Congenital: horseshoe kidney affecting about 1 in 400 people in which a person"s two kidneys fuse together to form a horshoe-shape during development in the womb complications-kidney stones, urinary tract infections. Autosomal recessive polycystic kidney disease (arpkd) is much rarer than.
