HSS 1100 Lecture Notes - Lecture 2: Complement Membrane Attack Complex, Innate Immune System, Vacuum Cleaner

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: William Yan

Document Summary

Immunity= the protection against infectious disease conferred either by the immune response generated by immunization or previous infection or by other non-immunologic factors aka body"s ability to resist infection. 2 types of immunity: non- specific (innate, born with front line of defense, does not discriminate, specific (adaptive, acquired) Impermeable to most thing: most important part of innate immune system, dry, ph (acidic, secretes, sweat. Mucous membranes (mechanical: cilia in respiratory tract, lysozymes, ph. Iron-binding proteins: some bacteria require iron for growth, transferrin, lactoferrin. Phagocytes: pmns, monocytes and macrophages, foreign bacteria attacker, we have wbc that is a good general vacuum cleaner. Complement (important: what it is, and 2 things it can do, set if circulating proteins in the blood, functions, can bind to antibodies. When innate immune system can do its job, we need: Specific immunity: directed against one specific type of invader. What is the difference between innate and immunity and adaptive immunity.