HSS 2305 Lecture Notes - Lecture 9: Euchromatin, Epigenome, Epigenetics

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 2305
• Professor: Shannon Bainbridge

Document Summary

Lecture 9 gene environment interactions; epigenetics (oct 5) Structure of dna strand of nucleotide as well as proteins. Compact dna by wrapping histones, wrapping these histones around other histones. Dna + proteins (dna and histones that its wrapping around) Made up of h2a, h2b, h3, h4 (proteins) Diff proteins change histones to open up dna. For the most part are positively charged. Dna backbone is negatively charged; this is how they interact. Little strand of amino acids that stick out. H1 linker molecule b/w diff wraps of dna; not found in the core. Controversy on this (not sure which of these two formations occur) Methyl groups or acetyl groups can be placed on amino acids of tails. Depending on which amino acid, whether acetyl or methyl totally diff response. Modifications are superficial sitting on top of genetic code; nucleotides stay the same. As twins age epigenetics differ, especially if lifestyles are very different.