HSS 2342 Lecture Notes - Lecture 21: Cori Cycle, Acetyl-Coa, Pyruvic Acid

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 2342
• Professor: Keir J Menzies

Document Summary

Catabolism: carbon, hydrogen, oxygen, nitrogen, glucose (6-c, glycerol (3-c, fatty acids (16-c and 18-c, amino acids (2, 3, or more c + n, https://youtu. be/vuilsn32wae. Different paths, lead to: pyruvate, 3-c structure, used to make glucose, acetyl coa, 2-c structure, those converted to acetyl coa cannot make glucose but are readily able to provide energy and be used to make fat. Final energy pathways: tca cycle, electron transport chain. Cori cycle: anaerobic conditions (i. e. high energy demand), pyruvate-to-lactate. In this case, the demand for atp is so high and is needed so quickly, that we rely on anaerobic processes. The rate of glycolysis increases, and the hydrogen atoms produced are added to pyruvate to form lactate: lactate can then be released from the muscle, into the circulation to the liver. The cooh (carboxylic acid) is removed from pyruvate to yield a 2-c structure + co2. Cooh released as (cid:272)ar(cid:271)o(cid:374) dio(cid:454)ide i(cid:374) the lu(cid:374)gs.