HSS 2342 Lecture Notes - Lecture 23: Acetyl-Coa, Citric Acid Cycle, Lipogenesis
4 Apr 2018
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Document Summary
All of the energy-yielding nutrients can be broken down to acetyl coa. Acetyl coa can enter the tca cycle or it can make fat or ketone bodies. Many of these reactions release h atoms with their electrons, which are carried by coenzymes to the etc. In the end: o is consumed, water and carbon dioxide are produced, energy is captured in atp. Some amino acids, pyruvate, and glycerol can be used to make glucose. Fatty acids cannot be used to make glucose. Above only shows what happens during feasting ( ie protein can also be glucogenic but more during fasting circumstances). During times of feasting, metabolism tends to favour fat formation. Any additional protein becomes deaminated and the carbon skeleton used to make fatty acids. Cho ingested first replaces glycogen stores, then is oxidized, and finally can be converted to fat, although this new fat formation (de novo lipogenesis) occurs on a minor scale in comparison to the other processes.
