HSS 3101 Lecture Notes - Lecture 25: Ultraviolet, Confounding, Rickets
Document Summary
Provide evidence that exposure x leads to disease y. The contraction of disease y is caused by exposure to x. Making statements such as these are to goal of experimental research. X and y are related to each other they are also considered to be associated with each other. In 1822 it was thought that lifestyle changes, due to the industrial generation, result in more people getting rickets disease then before: life style changes, x, is the exposure which causes rickets disease, y. We know that the association between lifestyle and the disease are due to (mediated by) sunshine, vitamin d and calcium. Those that have a lifestyle where they are exposed to sunshine are less likely to get the disease because ultraviolet radiation (from the sun) generates vitamin d. There was an idea that the presence of the disease itself makes people change their lifestyle and remain indoors.