APA 3125 Lecture Notes - Lecture 5: Delayed Onset Muscle Soreness, Palpation, Ossification

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Primary and secondary injury: mast cells are the first activated. * this does not work for completely torn ligaments, surgery is necessary for complete ruptures because it cannot heal itself. Scar tissue begins forming 3-4 days post injury. Scar formation may take months, only 95% strength of original tissue: collagen maturation: re-organization of collagen on-going remodeling process, tensile strength of scar is proportional to, density of collagen fibers. Wolff"s law: tissue adaptation to imposed demands, mechanical loading (running, walking, training) response adaptive change hypertrophy increased tissue strength. Involves a direct attempt by the cortical bone to re-establish itself after interruption without the formation of a fracture callus: not common naturally- usually from surgical fixation, uses a pin or plate to heal the bone. Secondary bone healing: new bone is deposited to fill in the gap, natural bone healing, goes through similar steps of healing as soft tissues, reactive stage, lasts about 2-4 days.

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