MIC 4100 Lecture Notes - Lecture 1: John Wiley & Sons, Pattern Recognition Receptor, Natural Killer Cell

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Skin and mucous membranes protect your body and internal organs from injury and infectious agents: physical. These two physical barriers are made of cells that line body surfaces and secrete chemicals making the surface hard to penetrate and inhospitable to pathogen. Skins human beta-defensin-2 on human skin destroys pathogens by poking holes in bacterial membranes. Cuts, scratch, insects and animal bites, burn and other wounds can disrupt the intact skins make it vulnerable to infections. Mucous membrane or mucosa covers those tissues and organs of body cavity exposed to exterior. Function : prevent/flush invading microbes in different type of mechanical way. Coughing and sneezing physicals reflex flushing activities. Urinary flow- remove microbes in urinary tract, urinary infections commonly among those unable to empty their bladder completely or frequently enough. Tears and saliva flush bacteria from eyes and mouth. Vomiting and diarrhea- act to flush bacteria from digestive tract. Functions numbers of chemical barriers controls microbial growths.

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