PHS 3341 Lecture 17: Endocrinology 5&6 The Endocrine Pancreas and Diabetes Mellitus
7 Dec 2016
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Outline the structure and function of the endocrine pancreas. Exocrine (80%) : acini produce and secrete digestive enzymes and bicarbonate into a system of ducts. Exocrine (~1% weight of pancreas) ~2 million islets of langerhans: 4 types of cells which secrete their products directly into the bloodstream. Alpha and beta are the most important cell types. Stimulate body to do something with the glucose. Somatostatin: inhibits release of insulin and glucagon; slows digestive tract activity. Pancreatic polypeptide: regulatory role in secretory activity of exocrine pancreas and inhibits bile release by gallbladder. Summarize the role of insulin in regulating metabolic events during the absorptive. Glucagon (epinephrine, cortisol and growth hormone as well) You have either just eat, or you ate a few hours ago. Can only make proteins that are actively needed by the body. You are either in one state or the other. Remain in this stage until you eat again.
