PHS 4300 Lecture 2: PHS 2

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Phs 4300 b lecture 2 hypoxia edema lymphedema. Blood flow to tissues by arteries: any in supply of o2: hypoxia many reasons: Blood flow from tissues by veins: leads to venous engorgement, edema removal of co2 and wastes. Flow of lymph: accessory system of thin vessels allows excess fluid/plasma to diffuse between capillaries, interstitial spaces, and lymphatic vessels. Also plays a key role in immune system. Clot busters (eg tissue plasminogen activator tpa) When part of a thrombus breaks free and travels in the blood stream until getting lodged in a distal artery. It results in complete blockage (occlusion) of the artery. If the thrombi is from the left side of the heart there can be an ischemic stroke. Venous thrombi lungs, result in pulmonary embolism (pe). Rx: none/filters/tpa (ischemic strokes are tricky to deal w/)/surgery/ A sudden constriction of artery that causes flow obstruction. Cerebral; hemorrhagic ischemic stroke, or migraine (vasodilation after vasospasm)

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