PHS 4300 Lecture Notes - Lecture 6: Angular Cheilitis, Upper Gastrointestinal Series, Oral Candidiasis

• School: University of Ottawa
• Department: Physiology
• Course: PHS 4300
• Professor: Frank Feiner

Document Summary

Gi disorders: ingestion: process of taking food into digestive tract, propulsion (directional): mechanical: move food through gi tract. H2-blocker, (different from h1 cold: gastroesophageal reflux (gerd) & esophagitis. What is gerd: usually, pressure of ge sphincter & 20 peristalsis prevents backflow. Lining of esophagus = stratified squamous (need several layers so they aren"t damaged) * treatments: target for each stimulator is a proton pump each target: stimulateor or proton pump. * ppis (most effective) long-term use of ppis can lead to malabsorption of vitamin b12, iron, magnesium, calcium. * regulation of gastric secretion (i) neural (ach): long (vagus nerve) & short (enteric) reflexes (ii) hormonal: gastrin & histamine. Transition into epithelium stratified squamous simple columnar. Rolling (paraesophageal) hiatal hernia: 10%; part of greater curvature of stomach protrudes through 2nd or enlarged opening in diaphragm dont have ge out of position but area of stomach trapped above diaphragm cutting off blood supple (surgery)