PHS 4300 Lecture Notes - Lecture 9: Disseminated Intravascular Coagulation, Cardiac Arrhythmia, Lymphatic Vessel
Document Summary
Iv catheters (inflammation thrombophlebitis: risk factors, dehydration, heart failue, shock, aging, trauma, surgery, smoking, sedentary lifestyle, clinical manifestations, arterial: intermittent claudificaion (activity pain, venous: none/edema/life threatening pulmonary embolus. Intervention: address risk factors, prevent anticoagulant drugs (ex: heparin, clot busters (ex: tissue plasminogen activator tpa, surgical removal. )/surgery: other causes, fat (trauma/surgery), tumours (metastases), bacterial clumps, air (5- Reduced vascular flow: vasospasm, sudden constriction of the artery leads to flow obstruction, coronary: variant/prinzmetal angina, cerebral, hemorrhagic ischemic stroke, migraine (vasodilation after vasospasm) Inflammation: vasculitis (artery)/phlebitis (vein, causes: infection, adverse drug reaction, autoimmune, can be focus for thrombus formation, mechanical compression, trauma, casts/tight dressings, bleeding, edema. Blood/ lymphatic vessels: structural alterations: valvular incompetence, anteriosclerosis/atherosclerosis, arteriovenous fistula, artery/vein abnormally connected, brain arteriovenous malformation (avm, headache/dementia/seizures/bleed, lymphatic blockage. Pathogenesis strong link to smoking: amputation may be necessary, reynaud syndrome, extreme vasoconstriction cessation of flow to fingers/toes/earlobes/nose, also affects local nerve function pain and/or numbness. U/s, ct, mri, lymphoscintigram: rx: no cure.