PHS 4300 Lecture Notes - Lecture 3: Aortic Valve, Carditis, Hyperlipidemia

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Have unstable resting potentials called pacemaker potentials. Use calcium influx (rather than sodium) for rising phase of the action potential. All events associated with blood flow through the heart. Ischemia inadequate blood supply to a tissue. Necrosis death of body cells or tissues; myocardial cell necrosis can occur within 20 minutes after the beginning of ischemia (spontaneous cell death apoptosis) Stenosis pathological and permanent decrease in the diameter of a vessel, opening or hallow organ. Volume increase in a tissue or organ caused by an enlargement of the cells. Cardiac hypertrophy can develop normally following endurance exercises or pathologically following work overload. Selective hypertrophy of one of the cardiac chambers can occur. Slowing down of heart rate below 60 bpm. Results from endurance exercise, low body temp, drugs or parasympathetic activity. May also result from conduction disorders junctional rhythms. Acceleration of heart rate above 100 bpm. Caused by physical activity, elevated body temp, stress, drugs or heart disease.

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