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Lecture 11

PSY2301 Lecture 11: PSY 2301 - Feb 16 - SynapsesPremium

14 pages24 viewsSpring 2018

Department
Psychology
Course Code
PSY 2301
Professor
Patrick Davidson
Lecture
11

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How Do Neurons Communicate and Adapt?
The classical (oversimplified view)
- AP
- Release of well-understood neurotransmitter from bouton
- Travels across synapse to dendrite
- “Key in lock”
- Clear postsynaptic effect
- Clear link to psych, behaviour
Idiosyncratic naming…
Noun
- Dopamine (DA)
- GABA
- Norepinephrine (NE)
- Acetylcholine (ACh)
- Serotonin (5-HT)
Adjective (“ergic”)
- Dopaminergic
- GABAergic
- Noradrenergic
- Cholinergic
- Serotonergic

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A Chemical Message
- Loewi’s subsequent research
- Accelerator nerve: speeds up heart rate
- Epinephrine (EP, or adrenaline)
- Speeds heart rate in frogs
- Norepinephrine (NE, or noradrenaline)
- Speeds heart rate in mammals
- ACh, EP, and NE are also neurotransmitters in the CNS
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- Central and peripheral effects can be quite different
- Even within CNS (or PNS) can have different effects
- Depends on receptor
- Neurotransmitter
- Chemical released by a neuron onto a target with an excitatory or
inhibitory effect
- Outside the CNS, many of these chemicals circulate in the bloodstream as
hormones
- Hypothalamus → Pituitary Gland → Hormones → Target Organs and
Glands
The “typical” chemical synapse
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