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Lecture 13

PSY2301 Lecture 13: PSY 2301 - Mar 02 - Psychopathology

10 Pages

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Patrick Davidson

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How do Drugs and Hormones Influence the Brain and Behaviour? Outline: Principles of Psychopharmacology Mental Illness and Psychoactive Drugs Principles of Psychopharmacology Drugs Routes into the Nervous System Routes of Drug Administration Oral Safest, easiest, and most common route But also most complex More barriers that drugs must cross to have its desired effect Inhalation or injection Produces faster, more reliable, effects Fewer barriers for drugs to pass through BloodBrain Barrier (BBB) Helps prevent most substances, including drugs, from entering the brain via the bloodstream Endothelial cells in capillaries located throughout the body are not tightly joined, so it is easy for substances to move into and out of the bloodstream itself. In contrast, endothelial cells in the brain are tightly joined and the presence of astrocytes help keep most substances out BarrierFree Brin Sites Places that are easier to cross the BBB for drugs etc
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