ANT202H5 Lecture Notes - Lecture 9: Directional Selection, Birth Weight, Allele

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10 Nov 2016
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Changes relative frequency of allele over time. Filters does not create new genetic variation. Genotypic differences in ability to survive and reproduce. Fitness organisms probability of survival and reproduction. Relative fitness = measure of elative genetic contribution of genotype to next gen (w: genotypes = units of selection. Genotypes do not survive or reproduce = 0. Measure relative strength of selection acting against genotype. S=1: total selection against genotype, no contrition to next gen. Depends on differences in fitness b/t genotypes: differences large = effect of selection swong, allele frequencies change quickly from one generation to next. Increase or decrease variation within population: depends on type of selection and population initial allele frequencies. Reduces frequency of harmful recessive mutant allele: reduce variation. Frequency of advantages mutant allele: increases variation. Balancing selection: selection for heterozygote and against homozygotes, heterozygote most fit. Eg sickle cell: malaria common, heterozygote advantage. Stabilizing selection: selection against extreme values, maintain pop.

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