ANT202H5 Lecture Notes - Lecture 6: Genetic Information Nondiscrimination Act, Human Genome Project, Genetic Discrimination

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20 Aug 2017
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Precise id of full complement of human genes (~25, 000) Working specifically on n-code project: understanding organization of genetic networks & protein pathways. Proteome, pathways, networks & molecular systems that characterize life: understanding variation in human genome. Need detailed picture of genetic variation within/between human populations. Fundamental to understanding the phenotypic diversity observed in humans. Hapmap & 1000 genomes projects: understanding human evolution & evolution across species. Clarify role of different evolutionary factors in shaping genomes. Id genetic contributions to disease & drug response. Common, complex diseases = interplay of multiple genes & environmental factors. Id genetic factors contributing to good health & resistance to disease. Id allelic variants that protect against disease: develop approaches to predict disease susceptibility, drug response & early illness detection. Cheaper/more powerful diagnostic tests: developing new therapeutic approaches to disease. Id genetic factors in disease risk = new therapies.

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