BIO310H5 Lecture Notes - Lecture 8: Sliding Filament Theory, Neuromuscular Junction, Myocyte
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Lec 8 bio310 (note: lec 7 was the test)** Cross bridge how actin & myosin interact with each other to shorten muscle fibre. Without it, we can"t expose the myosin-binding site. The ca2+ is usually present in smooth er, also known as sarcoplasmic reticulum (sr). Impulse occurs thru motor nerve myelinated axon and axon terminal. The synaptic knob at nmj is known as the motor end plate. The nerve terminal is still myelinated by the schwann cell. Motor fibres are usually myelinated because we want the impulse to travel fast. The nerve terminal is just like the presynaptic membrane. Ca2+ will trigger vesicle opening to release nt. Active zones where nt vesicles are accumulated. Junction of folds where nt usually is released. The case at the nmj can also be considered as a synapse, but not between 2 neurons: Whenever the neuron ap arrives, the vesicles will be released. The receptors in skeletal muscles are nicotinic.
