BIO310H5 Lecture 19: LEC 19 BIO310
Document Summary
If instead of oxygen, co2 binds(binds to protein part), it"s called carbaminehemoglobin. Cooperativity: an oxygen bound to hemoglobin will enhance affinity of oxygen to hemoglobin it tries to get saturated hemoglobin will change conformation from a tensed state to a relaxed state once saturated. Relaxed = oxygen is easier given to molecule. Even with 95. 8% saturated, it will be considered fully saturated. If 50% of hemoglobin is bound to oxygen, the partial pressure will be 26. 8 pp. The more the oxygen there is, the greater the partial pressure will be. There"s also myoglobin: can also bind to oxygen. It binds to oxygen and is very unlikely to let the oxygen go, because muscle needs oxygen. It"s greedy for oxygen. oxygen curve will be much more to the left when compared to hemoglobin. Hemoglobin sees which tissue needs most oxygen and gives it. Fetal hemoglobin has higher affinity to oxygen: it doesn"t give oxygen away.
