BIO310H5 Lecture Notes - Lecture 11: Mitral Valve, Fetal Hemoglobin, Umbilical Cord

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11 Aug 2016
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Funny channels hyperpolarization change in membrane potential opening of ca channels (t-type) depolarization. Repolarization: closing of ca channel and opening of k channels or hyperpolarization. Pacemaker and contractile located in the heart. Pns decreases heart rate: effects k conductivity decreased ca conductivity, negatively effects t-type ca (close) and open k channels. Hyperpolarization increases distance between 2 action potentials. Sns increases heart rate: increased na and ca conductivity, ne (norepinephrine) or e ( epinephrine) phosphorylate funny channels easily open. Sns controls hr (heart rate) and contractions. Ne/e bind to g protein activate p. kinase phosphorylation of ca channels of l-type. Immediate excitation b/c of gap junction: actin and myosin. Av latent pacemaker: right atrium, ap (action potential) ventricle, excitation of atria reaches through av node thorough the bundle of his capillary muscle ( open and close valves) If the bundle of his removed: atria will contract but both ventricles would not contract.