BIO315H5 Lecture Notes - Lecture 15: Hydrolysis, Treadmilling, Reaction Rate Constant

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5 Dec 2017
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1: intermediate filaments: provide mechanical strength, rope-like structures. 3: actin filaments: help maintaining the cell and help in cell locomotion. Long, hollow cylinders made of the protein tubulin. Most highly concentrated in the cortex, just beneath the plasma membrane. 2 subunits coming together to form a dimer, 2 dimers coming together to form a tetramer. Special type inside the nucleus that lines the nuclear envelope called the nuclear lamina. Individual molecules that make up the cytoskeleton are in a constant state of flux. Cytoskeletal structure can change rapidly depending on need. Cytoskeleton helps to form specialized cell surface protrusions - microvilli. They help to maintain polarity within epithelial cells. They can promote adhesion b/w epithelial cells. Cytoskeletal filaments assemble from protein subunits that impart specific physical and dynamic properties. Intermediate - b/c subunits are elongated rather than globular this means that when you have many of them packed together you have a lot of lateral inhibition (side-side interaction)

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