BIO380H5 Lecture Notes - Lecture 1: Corpus Luteum, Microtubule, Chromatin
Document Summary
Lecture 1, 2 & 3: intro & structural and functional maturation of egg and sperm pgs. Gametogenesis: gametogenesis is sex cells converting into mature gametes; divided into four phases. Increase in the number of germ cells by mitosis: as soon as they are in the gonads, the primitive germ cells are called oogonia in female and spermatogonia in male. Rapid mitotic divisions to produce diploid progeny ( genetically equal: origin and migration of germ cells o. This phase is identical in both male and female. Primordial germ cells (pgc): earliest o precursors of gametes; arise outside of gonads and migrate into them during early embryonic development. Teratomas: misdirected pgcs that lodge in o extragonadal sites during migration usually die, but some of these cells survive. Reduce the number of chromosomes (2n n) Pgcs commence meiosis i in fetus (~5th month), and remain arrested as primary oocytes in prophase i until ovulation.
