BIO412H5 Lecture Notes - Lecture 3: Thyroid, Thyroglobulin, Anterior Pituitary
Document Summary
Th: some th responsive genes include, glucose transporters (glut1, na+,k+ atpase helps to generate heat, causes increase in metabolic rate. Bone - 99% of total body calcium: osteoblasts produce bone, osteoclasts resorb bone, 2. Gi tract calcium absorption: hormonal control, 1. Liver and muscle muscle is indirect via lactate & pyruvate: 2. Lipolysis: breakdown of triglycerides in adipose, 3. Insulin ( cells: glucagon ( cells, somatostatin ( cells) Insulin: stimulus for secretion is high blood glucose, secreted by cells, effect is to blood glucose, glucose in food stimulates release of insulin. Phosphate and glycolysis occurs to produce atp: atp sensitive k channel which inhibits and causes depolarization ca dependent release of insulin vesicles which allows insulin secretion, effects of insulin muscle and fat tissue. Insulin stimulates the synthesis of an enzyme (glucokinase: required to trap" glucose in the cell, any glucose coming in converted to glucose 6 phosphate but cannot go out and.
