BIO152H5 Lecture Notes - Lecture 11: Fgf4, Fgf19, Microphthalmia-Associated Transcription Factor
Document Summary
The tail and cap (integrity of the dna) After splicing - mrna is shorter (intron - intervening sequences between the exons) Contains 5" and 3" utr (allows translation to occur) A ribozyme (can fucntion as an enzyme) Rna may hydrogen-bond wiht other nucliec acids. If splicing does not occur properly - a nonfunctional protein. Sometimes introns have genes that are for gene expression. Alternative rna splicing (variety in how spliced) Proteins (have domains - divided on genes) Translation trna (transfer rna) - link between amino acid and codon. Structure of trna - amino acid attachment at 3". Ribosomes (3 docking - a(acceptor), p(peptidal), e - exit) Release factor - releases disassemble (requires atp) A gene dictates primary structure and primary structure dictates shape. Srp (signal reception protein) - docks the ribosome on er before translation) Transcription and translation same place and same time. More than 400 genetically distinct breeds worldwide. Mutation of fgs 4 (same gene in human - dwarfs)
