BIO153H5 Lecture Notes - Lecture 7: Mutation Rate, Phylogenetic Tree, Mutation

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24 Jan 2017
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Test: x multiple choic and 1 short answer. Show order in which they involve but not when they evolved. Becomes clear when you add time (how long a branch is becomes important) Number of mutations is proporitional to the time since divergence. We have a sense of how often these mutations occur. Mutation rate is the same in the phylogenetic tree. Second assumption: assume constant mutation rate across all taxa but it may not always be the change, may have changes, follow another model. Assume mutation rate stays same for longlonglong time. Neutral gene changes: no consequence so should be regular should be constant. Coding for a crucial protein or ability to do something. Most likely a deleterious mutation on that gene. Reduce fitness of individual and that gene -> does(cid:374)"t get tra(cid:374)slated i(cid:374) populatio(cid:374) and it doesn"t show up i(cid:374) (cid:373)utatio(cid:374) rate.