BIO200H5 Lecture Notes - Lecture 1: Chemical Substance, Xenobiotic, Pharmaceutical Drug

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28 Dec 2014
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Definition the science of drugs : a drug is: a chemical substance, not part of the normal diet, which affects an organism"s physiology. Query: drugs vs. foods? ( physiological vs pharmacological dose ) Note: in general, medicines normalize physiology, but any drug in excess = a. Note: drugs are: often organic compounds, often have a mw around 300 daltons, often affect excitable membranes (chemical messenger systems, ion channels, usually act by binding to proteins. References / sources of information: the pharmacological basis of therapeutics 11th ed, hardman et al. (eds. ) (2005): An excellent handbook, widely used by pharmacologists and doctors. (generally called. Goodman and gilman after the original editors. : compendium of pharmaceuticals and specialties: Issued annually, this canadian book is a compendium of product information supplied by the manufacturers. It also contains lists of manufacturers, addresses, etc. (called the. The american version of the cps. (called the pdr . : the merck index: