BIO315H5 Lecture Notes - Lecture 20: Proteoglycan, Vinculin, Hemidesmosome

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5 Dec 2017
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Distance moved is about 80 nm/ divided by time scale = approx. Measure the # of steps and divide by the distance = 8 nm: what would fig. With each step- the horizontal distance will be half as large, the slope will be steeper: you perform a separate experiment using actin and myosin. You obtain a trace that is identical to the one shown (b). Trick to this: focus on showing what the change is in the steps (vertical vs. horizontal) - how you will get marks. Cell junctions, cell adhesion and the extracellular matrix. Secreted in large amounts by connective tissues - provides strength and resistance. 42 collagen genes in the human genome. Type i - most common - found in bone. Elastin - major component of elastic fibers. Elastic fibers have fibrillin - glycoproteins that form scaffold proteins allowing elastin to deposit. Fibronectin and other glycoproteins help organize the matrix.

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