BIO380H5 Lecture Notes - Lecture 17: Notch Signaling Pathway, Stratum Basale, Stratum Corneum

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14 Feb 2018
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Epidermal differentiation: connections between basal lamina and the basal layer cells, here they are called the stratum (cid:271)asale are des(cid:373)oso(cid:373)es (cid:894)do(cid:374)"t (cid:374)eed to k(cid:374)o(cid:449) that(cid:895, general process is a wave, the top layer is dead cells. Immigrant cells in the epidermis: there are other cell types that populate the skin, but do not come from the ectoderm or the mesoderm. Skin isn"t only product of epidermis, we get our hair, our teeth, our mammary glands (females have these more developed: these derivatives are all extra things that can happen in addition. In the morphogenesis stage, they differ the most. Slide 10: different parts of our skin have different types of hair, the dermis determines what type of hair will form in the ectoderm, mesoderm will be deciding what the ectoderm will become (other appendages too) If you culture the ectoderm alone, it will not differentiate into epidermis.