PSY240H5 Lecture Notes - Lecture 2: Major Depressive Episode, Transgenerational Epigenetic Inheritance, Serotonin Transporter
Document Summary
= 2x more likely to develop mdd: genotype (diathesis) + stressful life events (stress) = 2x risk of major depressive episode (disorder, genes produce underlying vulnerability (diathesis, environment that precipitates or allows gene to be expressed (stress) Gene-environment correlation model: genetic endowment may increase the probability that an individual will experience stressful life events e. g. genetic vulnerability to developing blood-injury-injection phobia and impulsiveness. Impulsivity (genes) > recklessness, accident proneness > higher likelihood of injury = higher probability of developing blood-injury-injection phobia. Inherit mitochondrial dna from parents, specifically from mom: certain psychological disorders influenced by mtdna e. g. schizophrenia. Neurotransmitters: electrical signal from the axon of the presynaptic neutron triggers release of. Neurotransmitters from the axon: neurotransmitters diffuse across the synaptic cleft, neurotransmitters bind to receptors on the postsynaptic membrane (on the. Dendrites: triggers continuation/blocking/modulation of the electrical signal, some disorders involve dis regulation of neurotransmitters, parkinsons > glutamate doesn"t work.
