PSY201H5 Lecture Notes - Membrane Potential, Dementia, Mesolimbic Pathway

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Graded potentials stimulation of the nerve membrane can open ion channels in the membrane: na+ ions flowing in will depolarize the membrane (movement from , k+ ions flowing out of the membrane will hyperpolarize the membrane. 70mv to say 60mv) (-70mv to say 90mv) +40mv, producing the spike the restoration of the membrane potential to 70mn is produces by an opening of channels to k+ the ap is conducted along the axon toward the terminals o o. Details of the synapse cleft: space between the receptor sites of the dendrites and the terminal buttons. Neurotransmitters acetylcholine (ach: memory and learning don"t have to build the whole road, just have to repair it o sleep and dreaming disruptions in the ach process are responsible for. Alzheimer"s and dementia: necessary to send messages about motor movement, agonistic: mimic neurotransmitters, antagonistic: block neurotransmitters fills up all the receptor sites and blocks it from receiving ach dying from paralyzation.

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