PSY352H5 Lecture Notes - Lecture 6: Genetic Recombination, Genetic Linkage, Gamete
Document Summary
Variability reason why sexual reproduction prefered by natural selection. B/c if theres no variablility then its not adaptive when there are changes in the environment. Recombination can be used to identify the location of genes thru genetic mapping. Recombination: mitotic and meiotic cell division, use of genetic recombination as a tool to map genes. Mitosis: no recombination, 2 diploid cells (diploid produces diploid, occurs in somatic cells. Meiosis: produces 4 haploid cells (only one copy of each chromosome, occurs during gamete formation, recombination (portions of maternaal and paternal chromosome exchange) Exchange of genetic material b/w homologous chromosomes: basis of genetic diversity in sexually reproducing organisms. Recombination frequencies can be measured by genotyping individuals in a pedigree. Analysis of recombination frequency between two loci from one chromosome allows the estimation of the relative distance b/w them: higher frequency = genes further apart from each other.
