ANTC68H3 Lecture Notes - Lecture 10: Measles Virus, Mucus, Passive Immunity

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Earlier viewed by some as more dreaded than smallpox. Killed mostly the young ones (under the age of 10) Dramatic impact in virgin soil populations where it eliminated indigenous populations: virgin soil: agent has never been introduced to that population entire population is susceptible novel pathogen that is rendering the population. Relative benign disease with low childhood mortality in western societies. Formerly virgin soil communities in developing countries severe killer disease. Virus, very contagious, found in nasal secretion acquired through respiratory tract. Average incubation period = 10-14 days: patient is ineffective for 5 days before and after the attack. Requires very large populations for the disease remain endemic. In excess of 250,000 people: unlikely to have been a problem before agriculture and rise of cities. Measles mortality is highest in malnourished populations. But the multifactorial nature of nutrition and confounding with social factors make it impossible to define its importance specifically.

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