ANTC68H3 Lecture Notes - Antonie Van Leeuwenhoek, Soho, Miasma Theory
Document Summary
To determining disease outcomes: recognized seasonality of epidemics and treatments, believed in miasma (bad air) as a cause of disease, medical doctors still take the hippocratic oath. Anton van leeuwenhoek (1632 1723: father of microbiology, visualized bacteria under the lens of a basic microscope, important precursor to the germ theory. John graunt (1620-1674: bills of mortality, recognized seasonality of epidemics, the bills of mortality began late 1500"s after the plague, important source of demographic info via searchers. Edward jenner (1749-1823: father of immunology, 1796: inoculated boy with milkmaid"s cowpox blister"s pus injected boy with pus from active smallpox patient boy lived, vaccination eventually led to the eradication of smallpox. William farr (1807-1883: father of epidemiology, registrar general of london, bills of mortality, life table form of event history analysis. Provides life expectancy at birth/number of years remaining. A way to see how mortality changes with age. Winter 2013: precursor to international classification of disease (icd)
