BIOA01H3 Lecture Notes - Lecture 28: Nuclear Pore, Internal Ribosome Entry Site, Hydrolysis

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BIOA01H3 Full Course Notes
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BIOA01H3 Full Course Notes
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Lec 28: expression of genetic information (part ii) 3-dimensional shape, usually made of several secondary structure elements. Determined by the spatial distribution of hydrophilic and hydrophobic r groups along the molecule as well as by chemical bonds and interactions that form between the r groups. Hydrophobic r groups are close together away from water. Hydrophilic r groups are outside facing water. Many proteins are composed of multiple polypeptides that come together as subunits of a functional, large protein. Subunits assembled together to create the quaternary structure. Chaperones are proteins that bind newly made proteins and help them fold. Example: help hydrophobic r groups to fold and be away from water. Initiation in prokaryotes is at any shine-dalgarno sequence ; the mrna can be a. Shine-dalgarno sequence (5"-aggaggu-3") are just above aug codon polycistronic mrna that codes for several polypeptides. Ends with a stop codon where translation ends.

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