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Lecture 14

Lecture 14-15

13 Pages
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Department
Biological Sciences
Course Code
BIOA01H3
Professor
Mark Fitzpatrick

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Sanchika K
Nov.-23-10
Final Exam Notes Biology
Biology
Chapter 5: The Dynamic Cell Membrane
What are the Requirements for Life?
1.Supply of replicators- self-reproducing molecules
2.Replicator copy must be subject to error
3.Supply of free energy for metabolism/growth/reproduction/movement
4.Partial isolation from external environment
Why are membranes so important for Living Organisms?
Separate cell interior from external environment
Enclose cells and organelles inside cells
Responsible for selective permeability
Selection is really important allows for the ability of different concentration of material to
be found on different sides of the membrane
What is the structure of biological membranes?
Plasma membrane
Composed of 3 macromolecules
oLipids
www.notesolution.com
Sanchika K
Nov.-23-10
Final Exam Notes Biology
oProtiens
oCarbs
Key features
Lipids
Are insoluble in water
oNon polar hydrocarbon molecules go away from water
oHeld by weak hydrophobic forces
Major component of membranes
Phospholipids predominate
oPhosphate part is polar; hydrophilic
oFatty acid part is non-polar (uncharged) ; hydrophobic
oAmphipathic; membrane lipid has both hydrophobic and
hydrophilic part
oBi layer head is exposed to the outside tails are inside away from water
oSpontaneously orient themselves
Fluidity
oCrucial for function due to lipid
oPhospholipid can move laterally within the bilayer
Move, flip
oTypes of hydrocarbon tails
(unsaturated) less packed- leaky ; vegetable oil
saturated fatty acid tail (more packed)
oSteroid cholesterol
Has different effect on membrane fluidity at differ temp
www.notesolution.com
Sanchika K
Nov.-23-10
Final Exam Notes Biology
Good cholesterol made by body to keep membrane secure
Packs the spaced in unsaturated membrane
Membranes are more dynamic at temp; cholesterol fills the
space to prevent too much movement
Membrane Protein
Asymmetrically distributed in membrane
Can move freely within the bilayer or can be anchored to a specific region
Kinds/number vary amount different membranes
Involve in
oCatalyzing chemical rxn
oTransport processes
Types
oPeripheral- on 1 side of membrane only
oIntegral= trans membrane
Vertical transport
Carb
Oligosaccharide chains
Project from external surface of membrane
oGlycoproteins- attached to proteins
oGlycolipids- attach to phospholipids
Show considerable diversity and specificity
Function as a recognition signals between cells
www.notesolution.com

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Description
Sanchika K Nov.-23-10 Final Exam Notes Biology Biology Chapter 5: The Dynamic Cell Membrane What are the Requirements for Life? 1. Supply of replicators- self-reproducing molecules 2. Replicator copy must be subject to error 3. Supply of free energy for metabolismgrowthreproductionmovement 4. Partial isolation from external environment Why are membranes so important for Living Organisms? Separate cell interior from external environment Enclose cells and organelles inside cells Responsible for selective permeability Selection is really important allows for the ability of different concentration of material to be found on different sides of the membrane What is the structure of biological membranes? Plasma membrane Composed of 3 macromolecules o Lipids www.notesolution.comSanchika K Nov.-23-10 Final Exam Notes Biology o Protiens o Carbs Key features Lipids Are insoluble in water o Non polar hydrocarbon molecules go away from water o Held by weak hydrophobic forces Major component of membranes Phospholipids predominate o Phosphate part is polar; hydrophilic o Fatty acid part is non-polar (uncharged) ; hydrophobic o Amphipathic; membrane lipid has both hydrophobic and hydrophilic part o Bi layer head is exposed to the outside tails are inside away from water o Spontaneously orient themselves Fluidity o Crucial for function due to lipid o Phospholipid can move laterally within the bilayer Move, flip o Types of hydrocarbon tails (unsaturated) less packed- leaky ; vegetable oil saturated fatty acid tail (more packed) o Steroid cholesterol Has different effect on membrane fluidity at differ temp www.notesolution.com
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