BIOB10H3 Lecture Notes - Lecture 10: Cytoskeleton, Keratin, Cell Cortex

48 views12 pages
23 Sep 2016
School
Course
Professor

Document Summary

8nm diameter filaments: compared to 25nm microtubules. Microfilaments have polarity: end: pointed end, + end: barbed end. Polymerization of f-actin: actin monomers can be added to either end. When the concentration of monomers is high: occurs preferentially at the plus (+) end or barbed end. Occurs even when monomer concentrations are very low: requires energy. Hydrolysis of atp occurs sometime after polymerization. Similar to gtp hydrolysis by tubulin during mt assembly. Depolymerization of f-actin: occurs preferentially at the minus (-) end or pointed end, actin is constantly assembling and disassembling. As monomers are added preferentially to one end and removed preferentially from the other end: it appears as if monomers are moving towards one end (-) end, known as treadmilling. Myosins are motors that move along f-actin: move towards the plus (+) or barbed end, use atp to drive movement. Composed of: 1 pair of heavy chains.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents