BIOB10H3 Lecture Notes - Lecture 18: Prokaryotic Small Ribosomal Subunit, Stop Codon, Eukaryotic Initiation Factor

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12 Sep 2016
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Translation ii trnas and the genetic code mrnas. Transcribed from genes by rna polymerase ii: spliced capped and polyadenylated. Slide 5: figure a, important for exam. Molecular machines: require energy from gtp hydrolysis, the ribosomal rnas are key components to their function. Help select the trnas, bind protein factors, etc. The crystal structure of the ribosome (prokaryotic) helps us understand how this machine works. Each ribosome has three sites for association with trnas: a site. The anticodon ends of trnas contact the small subunit (30s) and therefore this part of the ribosome is involved in decoding the mrna: i. e. decoding site. The amino acid carrying ends of the trnas are found to contact the large subunit (50s: large subunit. The interface between the small and large subunit are mostly composed of rna: includes the catalytic site where peptide bond formation takes place.

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