BIOB11H3 Lecture Notes - Lecture 3: Absorbance, Isotopic Labeling, 28S Ribosomal Rna

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Neurospora; a bread mold that gene encodes a particular protein; if you have a mutant gene, then you do not have that enzymatic activity) Support for (cid:498)one gene/ one enzyme(cid:499) hypothesis (cid:523)in which a particular didn"t need many nutrients, knew it damage involved, it wouldn"t be able lot"s of stuff like amino acids, other had complex biomedical pathways; grown onto minimal medium. Some of the spores were taken and irradiated with (mutagens that can cause damage to dna; if there been to make that enzyme) It was then tested with other vitamins but only grew with pantothenic acid. In this case; mutation in gene encoding protein involved in making the vitamin pantothenic acid. If enz2 gene mutated, there is no. Enz2 to convert b to c; providing cells with c will (cid:498)rescue(cid:499), but providing a. Later, beadle & tatum"s results led to the (cid:498)one gene-one enzyme(cid:499) and b will not because the biomedical pathway would stop there hypothesis.

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