BIOB11H3 Lecture Notes - Lecture 9: Operon, Repressor, Recombinant Dna
Op 9: gene regulation i: promoters and control circuits. Smart pages: figs 12-1, 2, 3, 4, 33, 34, 44, 45, 48. Vocabulary words: operon/regulatory gene/repressor/inducer/co-repressor/derepression/ positive vs. negative control/cis vs. trans acting factors/deletion mutant/enhancer. Conversely, repressible operons are turned off when the appropriate metabolite (repressor) is present: cis refers to on the same strand". An example is a sequence of dna in the promoter/operator that controls a linked structural gene: trans" refers to across". They are often located far away from the gene they control and are orientation independent. The lac operon will be transcriptionally active under which of the following conditions: lactose present, glucose absent, lactose present, glucose present, lactose absent, glucose absent, lactose absent, glucose present, both a and b.