BIOB11H3 Lecture Notes - Lecture 16: S Phase, Sister Chromatids, Centrosome

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Lec 16: cell cycle ii: chromosome condensation & movement. Condensin: condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis. Lamina: the nuclear lamina is a dense (~30 to 100 nm thick) brillar network inside the nucleus of most cells. It is composed of intermediate laments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina regulates important cellular events such as dna replication and cell division. Centrosome: an organelle near the nucleus of a cell that contains the centrioles (in animal cells) and from which the spindle bers develop in cell division. Centrioles: a minute cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle bers in cell division. Spindle apparatus: spindle bers form a protein structure that divides the genetic material in a cell.

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