BIOB11H3 Lecture 7: BIOB10Y: Lecture 19; BIOB11: Lecture 7

In what specific ways can chromatin structure be modified, and how do these modifications influence eukaryotic gene expression?

How can enhancers influence the transcription of genes that are really far away on the same chromosome? What is the molecular composition of an enhancer (which biomolecule, and where is the enhancer found)?

Genetic traits are passed from parent to offspring via DNA replication prior to cell division. However, epigenetic modifications do not have the same copying mechanism. How could an epigenetic trait be maintained throughout multiple generations? Provide at least two examples.

What would be the effect of moving the insulato to a position between enhancer II and the promoter for gene B?

How do heterochromatin and histone modification cause telomeres to be epigenetically inherited?

Telomeres can have an epigenetic impact on inheritance. How might this happen and what might it have to do with heterochromatin and possibly histone modification