BIOB32H3 Lecture Notes - Lecture 7: Resting Potential, Goldman Equation, Alarm Clock
15 Apr 2019
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And neurones and other cells use these changes in mp to communicate information and stimulate various tasks to occur. Understanding the action potential: action potentials are triggered depolarizations, at the peak of the action potential, the membrane potential reverses sign, becoming positive inside stimulus. Then we have repolarization that brings membrane back down to resting potential, to a value lower than the initial resting potential (after hyper polarization: membrane more polarized than rmp). Then back to rmp (another ap: these aps/depolarizations require a stimulus: something to trigger ap to occur. Understanding the action potential: action potentials are triggered depolarizations, ligand-gated ion channels: Neurons are excitable: they can change their membrane ion permeability in response to stimuli, which leads to a change in their membrane potential: mechanically-gated ion channels, temperature-gated ion channels: Ligands could be neurotransmitters and we"d have neurotransmitter-gated channels that open in response to the binding of neurotransmitter.
